Descrizione Multiscala del Movimento della Linfa all'interno di un Linfonodo

Abstract:

" Lymph nodes are organs scattered throughout the lymphatic system which play a vital role in our immune response by breaking down bacteria, viruses, and waste; the interstitial fluid, called lymph once inside the lymphatic system, is of fundamental importance in this process as it transports these substances inside the lymph node. The main mechanical features of the lymph node include the presence of a porous bulk region (called lymphoid compartment), surrounded by a thin layer (called subcapsular sinus) where the fluid can flow freely. Lymph nodes are critical sites for the filtration and processing of lymph fluid, which contains a variety of immune cells, antigens, and other molecules. Understanding the fluid dynamics within lymph nodes is crucial for elucidating the mechanisms of immune response and for the development of therapies for lymphatic disorders.